Subcortical neglect as a consequence of a remote parieto-temporal dysfunction. A quantitative EEG study.
C Colson1, G Demeurisse, C Hublet
1Service de Revalidation Neurologique, CHU Brugmann, Brussels, Belgium. catherine.colson@chu-brugmann.be
Summary
Right hemisphere stroke patients with neglect show distinct right temporo-parietal cortical dysfunction. This study highlights the role of this specific brain region in the development of neglect syndrome following stroke.
Area of Science:
- Neuroscience
- Clinical Neurology
- Neurophysiology
Background:
- Neglect is a common deficit following right hemisphere stroke.
- A link between right temporo-parietal cortical dysfunction and neglect has been hypothesized.
Purpose of the Study:
- To investigate the relationship between clinical presentation and quantitative electroencephalography (EEG) data in right stroke patients.
- To identify EEG correlates of neglect in patients with right-sided brain lesions.
Main Methods:
- Quantitative EEG analysis using a 20-channel EEG cartography system.
- Calculation of delta and theta activities in 16 regions of interest.
- Comparison of EEG data between right stroke patients with and without neglect.
Main Results:
- EEG analysis revealed significant differences in the right parieto-temporal cortex between patients with and without neglect.
- Specific patterns of delta and theta activity in the right temporo-parietal region differentiated the two patient groups.
Conclusions:
- Right temporo-parietal cortical dysfunction is crucial for the development of neglect in patients with right subcortical damage.
- Intra-hemispheric network dysfunction within the right hemisphere contributes to neglect syndrome.
