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Related Experiment Videos

Spinal mast cell tumor in a dog.

Lisa E Moore1, Laura D Garrett, Brad Debey

  • 1Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan 66506, USA.

Journal of the American Animal Hospital Association
|January 24, 2002
PubMed
Summary

A mast cell tumor was found compressing the spinal cord in a Rottweiler, causing neurological deficits. This rare primary extracutaneous tumor occurred at the C6-T1 vertebrae, marking a first-time report for this specific location.

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Area of Science:

  • Veterinary Neurology
  • Canine Oncology
  • Comparative Pathology

Background:

  • Mast cell tumors (MCTs) are common in dogs, typically arising from the skin.
  • Extracutaneous MCTs are less frequent and can occur in various internal organs.
  • Spinal cord involvement by MCTs often presents as a secondary complication of systemic disease.

Observation:

  • A 6-year-old spayed female Rottweiler presented with progressive left forelimb lameness and subsequent tetraparesis.
  • Diagnostic imaging, including cervical myelography, revealed a mass compressing the spinal cord between the sixth cervical and first thoracic vertebrae (C6-T1).

Findings:

  • Necropsy confirmed a mast cell tumor as the cause of spinal cord compression.
  • Histopathological and gross examination indicated this was a primary extracutaneous mast cell tumor, with no evidence of cutaneous or other systemic involvement.

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  • This represents the first documented case of a primary MCT originating within the C6-T1 vertebral spinal cord region.

    • Implications:

    • This case expands the known anatomical locations for primary extracutaneous mast cell tumors in dogs.
    • Highlights the importance of considering spinal cord tumors in the differential diagnosis for dogs with progressive neurological deficits.
    • Underscores the need for thorough diagnostic investigation to differentiate primary spinal tumors from metastatic disease.