Camilla I Svensson1, Tony L Yaksh
1Department of Anesthesiology, University of California, San Diego, La Jolla, California 92093-0818, USA. csvensson@ucsd.edu
Spinal phospholipase A2 (PLA2) and cyclooxygenase-2 (COX-2) inhibitors reduce pain states. The primary pain relief mechanism involves modulating constitutive spinal COX-2, not upregulated forms.
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