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Delayed reactivation of haloperidol induced photosensitive dermatitis by methotrexate
G P Thami1, S Kaur, A J Kanwar
1Department of Dermatology and Venereology, Government Medical College and Hospital, Sector 32 B, Chandigarh 160047, India.
Postgraduate Medical Journal
|January 25, 2002
Abstract:
A man whose psoriasis was well controlled on methotrexate treatment developed pellagra-like photosensitive dermatitis when he started taking haloperidol. Reactivation of his dermatitis was observed with methotrexate as a recall photosensitivity phenomenon. This false photosensitivity reaction of methotrexate is an important but rarely encountered adverse effect. A possible interaction between methotrexate and haloperidol is emphasised.