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Published on: February 2, 2024
Cucurbitane, hexanorcucurbitane and octanorcucurbitane glycosides from fruits of Trichosanthes tricuspidata
Tripetch Kanchanapoom1, Ryoji Kasai, Kazuo Yamasaki
1Institute of Pharmaceutical Sciences, Faculty of Medicine, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima 734-8551, Japan.
Abstract:
From the fruits of Trichosanthes tricuspidata, 14 cucurbitane glycosides (khekadaengosides A-J, M-N, cucurbitacin J 2-O-beta-glucopyranoside and cucurbitacin K 2-O-beta-glucopyranoside), a hexanorcucurbitane glucoside (khekadaengoside K) and octanorcucurbitane (khekadaengoside L) were isolated along with two known cucurbitane glucosides (cucurbitacin 2-O-beta-glucopyranoside and 25-O-acetyl-cucurbitacin 2-O-beta-glucopyranoside). Structural elucidations were based on chemical and spectroscopic analyses.

