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Updated: Aug 18, 2026

A Murine Model of Hemodialysis Access-Related Hand Dysfunction
Published on: May 31, 2022
[The dilemma of the last vascular access]
P Petitjean1, S Boeriu, M Ismer
1Service de néphrologie et d'hémodialyse, Hôpitaux universitaires de Strasbourg.
Insights
Central venous catheters (CVCs) are crucial for hemodialysis but often malfunction. Salvage procedures like stripping and re-canalization offer effective solutions for CVC issues, improving patient access.
Area of Science:
- Nephrology
- Vascular Surgery
Context:
- Hemodialysis patients face challenges with vascular access due to age and cardiovascular disease.
- Central venous catheters (CVCs) are frequently used but prone to malfunction (87% of cases).
Purpose:
- To review salvage procedures for malfunctioning central venous catheters (CVCs) in hemodialysis.
- To evaluate the efficacy and complication rates of stripping and re-canalization techniques.
- To explore alternative vascular access sites.
Summary:
- Stripping removes fibrin strands around CVCs with 75-90% success.
- Re-vascularization techniques achieve 100% success in placing CVCs across thrombosed vessels.
- Alternative access sites include external jugular, femoral, and translumbar veins.
Impact:
- Improved management of CVC malfunction in hemodialysis patients.
- Enhanced vascular access strategies for challenging patient populations.
- Potential reduction in CVC-related complications and need for replacement.
Abstract:
Age and cardio-vascular pathologies in hemodialysis patients confront us with the increasing difficulties in finding vascular access. This implies the necessity to keep in place central venous catheters (CVC) and find alternative puncturing sites. CVC malfunction in dialysis is frequently encountered (87% of cases). A variety of salvage procedures are described in the literature amongst them the "stripping" and re-canalization methods. Stripping allows withdraw fibrin strands around the CVC with a success rate of 75 to 90% and a rather low complication rate, although this may not be well documented. Re-vascularization techniques allow the placement of a CVC even across a thrombosed vessel. Success rate here is 100% in a limited series of patients. In addition to the classical access sites, like internal jugular and subclavian vein exist, alternative sites such as the external jugular, femoral or even translumbar vein.
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