Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skeletal tissue engineering: opportunities and challenges.

F P Luyten1, F Dell'Accio, C De Bari

  • 1Laboratory for Skeletal Development and Joint Disorders, Onderwijs & Navorsing, Department of Rheumatology, University Hospitals, Herestraat 49, KU, Leuven, Belgium.

Best Practice & Research. Clinical Rheumatology
|January 29, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effects of a sleeve knee brace during stair negotiation in patients with symptomatic patellofemoral osteoarthritis.

Clinical biomechanics (Bristol, Avon)·2023
Same author

Cellular therapy and tissue engineering for cartilage repair.

Osteoarthritis and cartilage·2022
Same author

Bio-optimized Curcuma longa extract is efficient on knee osteoarthritis pain: a double-blind multicenter randomized placebo controlled three-arm study.

Arthritis research & therapy·2019
Same author

Advancing osteochondral tissue engineering: bone morphogenetic protein, transforming growth factor, and fibroblast growth factor signaling drive ordered differentiation of periosteal cells resulting in stable cartilage and bone formation in vivo.

Stem cell research & therapy·2018
Same author

Pharmacological blockade of the WNT-beta-catenin signaling: a possible first-in-kind DMOAD.

Osteoarthritis and cartilage·2017
Same author

Toward classification criteria for early osteoarthritis of the knee.

Seminars in arthritis and rheumatism·2017

Tissue engineering advances skeletal tissue regeneration for clinical applications like joint repair. Further research is needed to ensure the consistency, reproducibility, and regulation of these novel regenerative medicine treatments.

Area of Science:

  • Biomedicine
  • Developmental Biology
  • Cell Biology
  • Biomaterial Sciences

Background:

  • Tissue engineering is a rapidly advancing field crucial for biological tissue repair.
  • Skeletal tissue regeneration, including joint resurfacing, shows significant clinical potential.
  • Novel tools like stem cells and gene transfer technologies offer new therapeutic avenues.

Purpose of the Study:

  • To explore the potential of tissue engineering in skeletal tissue regeneration.
  • To highlight the role of advanced biological and material sciences.
  • To emphasize the need for rigorous validation in regenerative medicine.

Main Methods:

  • Leveraging advances in developmental and cell biology.
  • Utilizing novel biomaterials and smart biomaterials.

Related Experiment Videos

  • Employing pluripotent stem cells and gene transfer technologies.
  • Main Results:

    • Tissue engineering offers promising approaches for skeletal tissue repair and joint resurfacing.
    • The integration of various scientific disciplines accelerates regenerative medicine.
    • Emerging technologies enable innovative therapeutic strategies.

    Conclusions:

    • Tissue engineering holds great promise for skeletal tissue regeneration and clinical applications.
    • The clinical translation of these technologies requires careful consideration of consistency, reproducibility, and validation.
    • Regulatory frameworks are essential for the safe and effective implementation of regenerative medicine treatments.