Related Experiment Video
Updated: Jul 6, 2026

Modeling Chemotherapy Resistant Leukemia In Vitro
Published on: February 9, 2016
Pain and leukemia: the stories of three children
Elizabeth A Bossert1, Lois Van Cleve, Kathleen Adlard
1Loma Linda University School of Nursing, Loma Linda, CA 92350, USA.
Abstract:
The stories of the pain experience of three children with acute leukemia during the first year after diagnosis are presented in this report. To provide a broad picture, children who represent various characteristics were selected: ages 6, 9, and 15 years; two male and one female; two Latino and one Caucasian; two English-speaking and one Spanish; two with acute lymphocytic leukemia and one with acute myelocytic leukemia. Consideration of the disease, procedures, treatment, and normal childhood pain experiences will provide the nurse who cares for these children guidance in knowing why and when pain may occur, which will lead to timely interventions for the pain.
Related Concept Videos
Rous Sarcoma Virus (RSV) and Cancer
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
Stem Cell Therapy for Tissue Regeneration
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Blood and Nerve Supply to the Bones
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Disorders of Leukocytes
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

