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Paranasal sinus mucormycosis: a report of two cases

P Ruoppi1, A Dietz, E Nikanne

  • 1Department of Otorhinolaryngology, Kuopio University Hospital, Finland. pirkko.ruoppi@kuh.fi

Acta Oto-Laryngologica
|January 30, 2002
PubMed

Insights

Nasal mucormycosis is a rare fungal infection, often fatal, affecting immunocompromised individuals. Successful treatment involves surgical debridement and amphotericin B, even in some immunocompetent patients with predisposing factors.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Otolaryngology

Background:

  • Mucormycosis of the nose and paranasal sinuses is a rare, aggressive fungal infection.
  • It predominantly affects immunocompromised individuals, often linked to diabetic ketoacidosis.
  • Local factors like chronic sinusitis can predispose even immunocompetent individuals.

Observation:

  • Two cases are presented: one immunocompetent patient with prior polypous rhinosinusitis, and one with mild adult-type diabetes.
  • Both cases exhibited the characteristic fulminant course of sinonasal mucormycosis.

Findings:

  • Successful treatment was achieved through surgical debridement and administration of amphotericin B.
  • Correction of underlying metabolic disorders is crucial for improving prognosis.

Implications:

  • This highlights the importance of prompt diagnosis and aggressive management of sinonasal mucormycosis.
  • Effective treatment strategies, including surgery and antifungal therapy, can lead to favorable outcomes even in complex cases.

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