Simulation study of a selective cerebral perfusion system with a single centrifugal pump

We previously successfully developed a simple nonroller extracorporeal circulation system (NRECC). In aortic arch surgery, more than two pumps are generally used for systemic perfusion and selective cerebral perfusion (SCP); we developed a new pressure-dependent perfusion system for SCP based on our NRECC and operated by a single centrifugal pump. The cerebral perfusion line was branched from the main perfusion line, and one 15 French and two 12 French cannulae were used for SCP. The perfusion pressure was regulated with a tube occluder. Afterload was changed from 30 to 80 mm Hg, the pressure of the SCP line was increased from 80 to 200 mm Hg, and flow volume was measured. When the afterload was set at 50 mm Hg, according to the increase of perfusion from 80 to 200 mm Hg, the flow volume of the 15 French cannula increased from 280 to 950 ml/min. Under the same conditions, flow volume of the 12 French cannula increased from 160 to 560 ml/min. Sufficient flow volume of the SCP lines was obtained when the SCP line pressure was over 80 mm Hg. As a result of the increased perfusion pressure, the flow volume showed a direct increase. These findings suggest that aortic arch surgery is possible using this SCP system.