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7-Methoxyfuro[2,3-c]pyridine-4-carboxamides as PDE4 inhibitors: a potential treatment for asthma
George M Buckley1, Nicola Cooper, Richard J Davenport
1Celltech R & D, Granta Park, Great Abington, Cambridge CB1 6GS, UK.
Bioorganic & Medicinal Chemistry Letters
|January 30, 2002
Abstract:
The synthesis and pharmacological profile of a novel series of 7-methoxy-furo[2,3-c]pyridine-4-carboxamides is described. Some of these compounds were found to be potent inhibitors of phosphodiesterase type 4 (PDE4).