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Updated: Jul 28, 2026

Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells
09:03

Monitoring Functionality and Morphology of Vasculature Recruited by Factors Secreted by Fast-growing Tumor-generating Cells

Published on: November 23, 2014

[New observations support the significance of angiogenesis in myeloma]

L G Lundberg1, R Lerner, J Palmblad

  • 1Medicinkliniken, Södersjukhuset och institutionen Södersjukhuset, Karolinska institutet, Stockholm.

Lakartidningen
|January 31, 2002
PubMed

Angiogenesis appears to be a prominent feature of many hematological disorders, in particular multiple myeloma. The remissions achieved when treating patients with advanced myeloma with the angiostatic drug thalidomide suggested that the disease might be angiogenesis-dependent. However, the mechanisms for the beneficial effect of thalidomide are, at this time, rather unclear, and may involve other effects beside angiostasis. Nonetheless, these and other observations have spurred an interest in angiogenesis that might lead to new concepts and treatment modalities. Here, an update concerning angiogenesis and multiple myeloma is presented.

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