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Updated: Oct 2, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
Preterm premature rupture of the fetal membranes complicated by oligohydramnios
1Pregnancy and Perinatology Branch, Center for Research for Mothers and Children, NICHD, National Institutes of Health, Bethesda, Maryland, USA. spongc@exchange.nih.gov
Abstract:
Preterm premature rupture of the fetal membranes complicated by oligohydramnios may have significant impact and sequelae on pregnancy outcome. In this article the role of amniotic fluid in fetal development, especially lung development, is reviewed; complications resulting from oligohydramnios are outlined; and the evaluated therapeutics and management schemes are delineated.
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