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[Evidence based medicine with reference to the aging man].

E Plas1, J W Thüroff, H Pflüger

  • 1Abteilung für Urologie, Ludwig-Boltzmann-Institut für Urologie und Andrologie des Krankenhauses der Stadt Wien Lainz. ple@uro.khl.magwien.gv.at

Wiener Medizinische Wochenschrift (1946)
|January 31, 2002
PubMed
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Hormonal substitution may improve quality of life in ageing men, but more long-term, evidence-based research is needed. Current data is insufficient to fully evaluate the benefits of hormone replacement therapy in men.

Area of Science:

  • Gerontology
  • Endocrinology
  • Male Reproductive Health

Context:

  • Growing public and medical interest in male ageing.
  • Challenges in maintaining physical and mental fitness in older men.
  • Hypothesis of hormonal alterations contributing to ageing in males.

Purpose:

  • To explore the potential of hormonal substitution to enhance quality of life and longevity in ageing males.
  • To assess hormonal therapies based on evidence-based medicine principles.
  • To identify gaps in current research regarding male ageing and hormone therapy.

Summary:

  • Ageing males experience hormonal changes, suggesting hormone substitution as a potential intervention.
  • Evidence-based medicine requires robust clinical experience and scientific data, including long-term studies.

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  • Current research lacks sufficient long-term data and large patient cohorts to definitively evaluate hormonal substitution's value in ageing men.

    • Impact:

    • Highlights the need for rigorous, long-term clinical investigations in male ageing.
    • Emphasizes the importance of evidence-based medicine for patient care decisions.
    • Underscores the incomplete understanding of pathophysiological changes during male ageing.