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Clinical aspects of infantile asthma

G W Brasher

    Annals of Allergy
    |October 1, 1975
    PubMed

    Insights

    Infantile asthma, a common respiratory issue in infants, often involves wheezing and can be linked to food allergies. Early identification of atopic diathesis through eosinophilia aids in management, with dietary changes being a primary intervention.

    Area of Science:

    • Pediatrics
    • Allergology
    • Immunology

    Background:

    • Infantile asthma poses significant challenges for physicians.
    • Recurrent wheezing is a common symptom in infants as young as seven months.

    Purpose of the Study:

    • To explore the characteristics and management of infantile asthma.
    • To identify factors influencing allergic respiratory disease in infants.

    Main Methods:

    • Analysis of clinical presentation in infants with asthma.
    • Assessment of eosinophilia in peripheral blood and nasal secretions.
    • Evaluation of the role of food allergens in infantile asthma.

    Main Results:

    • 47% of infants with asthma show peripheral blood or nasal eosinophilia, indicating atopic diathesis.
    • Younger infants are more likely to have food as a significant factor in their allergic respiratory disease.
    • Wheezing persistence in childhood correlates with positive nasal smears during initial allergy evaluation.

    Conclusions:

    • Early identification of atopic diathesis is crucial for managing infantile asthma.
    • Dietary manipulation is a key initial treatment, with hyposensitization considered for non-responders.
    • Nasal smear results are important predictors of persistent wheezing in childhood.

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