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[Correlation between birefringence and histopathologic figures of keratoconus and bullous keratopathy]
Sonoko Tamura1, Shigekuni Okisaka, Akira Momose
1Department of Ophthalmology, National Defense Medical College, 3-2 Namiki, Tokorozawa 359-8513, Japan.
Purpose:
We studied macroscopic pictures with polarizing filter and microscopic pictures of the corneas in keratoconus and bullous keratopathy.
Method:
Among penetrating keratoplasty specimens referred to the National Defense Medical College, we investigated 16 keratoconus and 189 bullous keratopathy specimens. Macrophotographs with polarizing filter and light microscopic photographs (hematoxylene-eosin staining) were investigated. The hyperbolic polarizing pattern, stromal thickness of corneal specimens and number of fibroblast-like cells in the stroma were analyzed.
Result:
Hyperbolic polarizing patterns depended on the number of fibroblast-like cells in the stroma and the thickness of the stroma, but hyperbolic polarizing patterns had no relation with the epithelium or endothelium of the cornea.