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Updated: Aug 19, 2026

Quantitative Mass Spectrometric Profiling of Cancer-cell Proteomes Derived From Liquid and Solid Tumors
Published on: February 27, 2015
Methods of molecular analysis: assessing losses and gains in tumours
1Molecular and Population Genetics Laboratory, Imperial Cancer Research Fund, London, UK. r.roylance@icrf.icnet.uk
Abstract:
The study of chromosomal aberrations has facilitated the understanding of tumorigenesis. By applying molecular genetic techniques to regions highlighted by cytogenetic study, many genes important in tumorigenesis have been identified. This review will describe the cytogenetic and molecular cytogenetic techniques used to identify these changes. The clinical information that they can provide, including diagnostic and prognostic information, will also briefly be discussed.

