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Olfactory acuity after total laryngectomy.

Megumi Fujii1, Keijiro Fukazawa, Chihiro Hatta

  • 1Department of Otorhinolaryngology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan. megumi@hyo-med.ac.jp

Chemical Senses
|February 13, 2002
PubMed
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Laryngectomy patients showed temporary olfactory acuity decline, but function returned to normal within 6-12 months. Nasal tissues may atrophy, but olfactory epithelium remains intact post-surgery.

Area of Science:

  • Otolaryngology
  • Neuroscience
  • Surgical Research

Background:

  • Laryngectomy, a surgical procedure for voice restoration, can potentially impact olfactory function.
  • Understanding post-laryngectomy olfactory changes is crucial for patient quality of life.

Purpose of the Study:

  • To prospectively evaluate olfactory acuity in patients following laryngectomy.
  • To assess the impact of laryngectomy on nasal and olfactory mucosa.

Main Methods:

  • Olfactory acuity was measured using the Jet Stream Olfactometer (JSO) and Alinamin test.
  • Nasal and olfactory mucosa were examined via rigid endoscopy.
  • Evaluations were conducted preoperatively and at 3, 6, and 12 months post-surgery in 29 patients.

Related Experiment Videos

Main Results:

  • Olfactory detection and recognition thresholds temporarily increased at 3 months post-surgery.
  • Significant differences were noted between preoperative and 3-month postoperative thresholds.
  • No significant differences in olfactory thresholds were found at 6 or 12 months compared to preoperative values.
  • Atrophic nasal respiratory mucosa was observed in 11/14 patients at 12 months, while olfactory mucosa remained normal.

Conclusions:

  • Olfactory epithelium function appears to remain intact after laryngectomy.
  • Temporary olfactory impairment may occur, but recovery is likely within 6-12 months.
  • Nasal mucosal changes post-laryngectomy do not necessarily affect olfactory function.