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Controlled Odor Mimic Permeation Systems for Olfactory Training and Field Testing
Published on: January 28, 2021
Odor Sampling Bags Enable Reliable Delivery of Controlled Odor Concentrations
Matthew Andres1, Robert Pellegrino1,2, Xuebo Song1
1Monell Chemical Senses Center, Philadelphia, PA, USA.
Chemical Senses
|July 28, 2026
Summary
A novel odor sampling bag system using Nalophan plastic offers a reliable method for olfactory research. This system enhances stimulus consistency by eliminating solvent interactions and ambient air dilution, improving odor concentration control.
Area of Science:
- Olfactory research
- Psychophysics
- Sensory science
Background:
- Precise control of odorant concentration is crucial for reliable olfactory research.
- Existing odorant delivery methods face challenges like solvent interactions and ambient air dilution, compromising stimulus consistency.
Purpose of the Study:
- To develop and validate a novel odor sampling bag system for accurate odorant concentration delivery.
- To compare the performance of the new system against traditional glass jars in terms of perceptual intensity and reliability.
Main Methods:
- Development of an odor sampling bag system using Nalophan plastic with air as the carrier medium.
- Two experiments involving 15 participants rating perceived intensity of benzaldehyde and 2-heptanone at seven concentrations using both bags and glass jars.
- Photoionization detector measurements to confirm headspace concentration stability over time.
Main Results:
- Odor sampling bags yielded significantly higher maximum perceptual intensities (p < 0.001) compared to glass jars.
- Bags demonstrated superior test-retest reliability (Experiment 1: r = 0.89 vs. 0.81; Experiment 2: r = 0.86 vs. 0.72).
- Odorant-specific concentration differences were better preserved in bags, unlike in jars.
Conclusions:
- The Nalophan plastic odor sampling bag system provides an affordable, reliable, and accurate method for delivering controlled odor concentrations.
- This system eliminates solvent variability and ambient air dilution, enhancing stimulus consistency in olfactory psychophysics research.
- The method offers a practical alternative to expensive olfactometry equipment for precise odor delivery.

