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Related Experiment Videos

Primary malignant large bowel lymphoma.

Manoj Pandey1, Kiran C Kothari, Manish K Wadhwa

  • 1Department of Surgical Oncology, Gujarat Cancer and Research Institute, Ahmedabad, India.

The American Surgeon
|February 15, 2002
PubMed
Summary

Large bowel lymphoma is a rare but curable cancer. Aggressive treatment with surgery and chemotherapy offers a good prognosis, with a 4-year disease-free survival of 66.7%.

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Area of Science:

  • Gastroenterology
  • Oncology
  • Pathology

Background:

  • Primary gastrointestinal (GI) lymphomas are rare, with large bowel involvement being even rarer.
  • This study investigates the prevalence and characteristics of large bowel lymphoma.

Purpose of the Study:

  • To evaluate the prevalence and clinicopathological features of large bowel lymphoma.
  • To compare findings with existing literature.

Main Methods:

  • Retrospective analysis of 8 histologically diagnosed large bowel lymphoma cases over 5 years.
  • Diagnosis confirmed via colonoscopic biopsies.
  • Treatment involved surgery and adjuvant chemotherapy.

Main Results:

  • Large bowel lymphoma accounted for 12.3% of all GI lymphomas studied.

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  • Mean age at presentation was 30.6 years, with a 1:2 male-to-female ratio.
  • Altered bowel habits and diarrhea were common symptoms; 4-year disease-free survival was 66.7%.

    • Conclusions:

    • Large bowel lymphoma is a curable malignancy with aggressive management.
    • Primary surgery followed by adjuvant chemotherapy is recommended for all patients.