[Thrombocytic lipids in different clinical manifestations of myocardial infarction]

The stady was made of changes in lipid composition of platelet membranes in various clinical manifestations of myocardial infarction (MI). Phospholipids, cholesterol and its ethers in platelet membranes were studied which thinlayer chromatography in 98 MI patients aged 30-60 years and 20 healthy subjects aged 32-56 years. In acute MI platelet membrane shows metabolic disturbances while subacute phase and scarring are characterized by positive membrane processes. In lethal MI membrane disembolism is irreversible. Thus, membrano-destructive alterations in platelets correlate with MI clinical symptoms and outcome.