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Use of Freeze-thawed Embryos for High-efficiency Production of Genetically Modified Mice
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[Genetic modification of animals]
1Gemeenschappelijk Dierenlaboratorium, Centrum voor Natuurwetenschap en Innovatiemanagement, Universiteit Utrecht, Bolognalaan 50, 3584 CJ Utrecht.
Tijdschrift Voor Diergeneeskunde
|February 23, 2002
Summary
Genetic modification of animals, using techniques like transgenesis and cloning, has been vital in biotechnology since the 1970s. Legislation addresses the associated risks and applications of these genetically modified animals.
Area of Science:
- Biotechnology
- Animal Genetics
- Molecular Biology
Context:
- Genetic modification of animals has been a cornerstone of modern biotechnology since the 1970s.
- Traditional selective crossbreeding has been augmented by advanced techniques like transgenesis, gene targeting (knock-out animals), and cloning.
- These technologies enable precise control over animal traits.
Purpose:
- To outline the evolution and current state of animal genetic modification.
- To detail the various fields where genetically modified animals are applied.
- To address the regulatory landscape concerning the risks and management of genetically modified animals.
Summary:
- The abstract discusses the historical development and modern applications of genetically modified animals in biotechnology.
- It highlights key techniques such as transgenesis, knock-out animal models, and cloning.
- The text also touches upon the fields of application and the legislative framework established to mitigate potential risks.
Impact:
- Provides an overview of genetic modification in animals, crucial for researchers and policymakers.
- Highlights the importance of regulatory frameworks in managing biotechnological advancements.
- Informs about the applications and risks associated with genetically modified animals in science and industry.
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