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Updated: Aug 5, 2026

High-Resolution Endocardial and Epicardial Optical Mapping in a Sheep Model of Stretch-Induced Atrial Fibrillation
Published on: July 29, 2011
[Structural and electrophysiological characteristics of the heart function during paroxysmal atrial fibrillation]
Aim:
To examine structural and electrophysiological predictors of the onset and establishment as chronic of cardiac fibrillation (CF).
Material And Methods:
Echocardiography, transesophageal electrophysiological examination of the heart were performed in 420 cases of paroxysmal cardiac fibrillation (PCF). They were diagnosed as having new-onset (n = 68), rare (n = 92) and frequent (n = 260) PCF.
Results:
Compared to healthy subjects, PCE patients had larger size of the left atrium (LA), higher atrium/ventricle value, lower frequency threshold of arrhythmia induction, decreased left atrial effective refractory period, longer induced paroxysm and maximal atrial response. CF chronicity can be predicted with the frequency threshold of arrhythmia induction under 300 imp/min, left atrial effective refractory period under 220 ms, left atrial size over 42 mm, induction of persistent PCF.
Conclusion:
A significant correlation was found between left atrial size and electrophysiological parameters of the heart characterizing arrhythmogenic "readiness" of the atria. This suggests a provoking role of left atrial dilatation in PCF.
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