Related Experiment Videos
[Evaluation on the effect of Benazepril for hypertension through postmarketing surveillance]
Objective:
To evaluate the efficacy and safety of Benazepril used among the essential hypertensives.
Methods:
1 831 essential hypertensive patients aged 35 to 75 were randomly selected from a community and followed for 18 months. The level of blood pressure, status of taking Benazepril and side effects were sequencially collected.
Results:
1/3 of the patients had taken antihypertensive drug before the study and the rate of compliance was over 96%. The effective rate of Benazepril was 73.6% at three months and increased to 84.7% at 18 months. Comparing with the baseline data, SBP and DBP declined 10.8 mmHg and 6.7 mmHg respectively. The rate of side effect was 22.7%. Cough was most commonly seen among side effects. The peak of first recording on side effect occurred at three months including 60% of them mild.
Conclusion:
Results showed that Benazepril had good efficacy and safety for the essential hypertension patients in a long-term observation.
Related Concept Videos
Pharmacovigilance
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors
Hypertension III: Clinical Manifestations and Diagnostic Studies
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System
Antihypertensive Drugs: Angiotensin II Receptor Blockers
Antihypertensive Drugs: Action of β1 Blockers