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Venous leg ulcer: incidence and prevalence in the elderly
David J Margolis1, Warren Bilker, Jill Santanna
1Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104, USA. dmargoli@cceb.med.upenn.edu
Background:
Venous leg ulcer is a disease most common in those aged 65 years and older. However, the incidence and prevalence have not been well established.
Objective:
Our purpose was to estimate the prevalence and incidence of venous leg ulcers in the elderly.
Methods:
We studied the General Practice Research Database, validated our case ascertainment strategy, and estimated the annual prevalence and incidence of venous leg ulcer.
Results:
The positive predictive value of our ascertainment strategy was 98.3% (95% confidence interval [CI], 90.0, 100.0). The annual prevalence of venous leg ulcer among the elderly was 1.69 (95% CI, 1.65, 1.74). The overall incidence rate was 0.76 (95% CI, 0.71, 0.83) for men and 1.42 (1.35, 1.48) per 100 person-years for women.
Conclusion:
Venous leg ulcer is a significant problem in those aged 65 years and older. As compared with previous studies, because we used medical records from a population of known size, our results are precise and less biased.