Functional changes in temporal lobe activity during transient global amnesia
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Updated: Oct 2, 2026

Investigations on Alterations of Hippocampal Circuit Function Following Mild Traumatic Brain Injury
Published on: November 19, 2012
Kevin S LaBar1, Darren R Gitelman, Todd B Parrish
1Center for Cognitive Neuroscience, Duke University, Durham, NC 27708-0999, USA. klabar@duke.edu
Abstract:
The integrity of temporal lobe activity during and after recovery from transient global amnesia (TGA) was assessed in a case study using functional MRI. TGA was associated with scene-encoding deficits in a temporolimbic circuit that recovered over time. Frontoparietal areas recruited during the amnesic state may signify a compensatory reliance on visuospatial or working memory strategies. Reduction of extrastriate cortex responses over repeated testing sessions possibly indicates intact visual priming in TGA.
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