Children born from pregnancies complicated by subnormal oestriol excretion--first year

This paper is the first of a series concerning the follow-up of children whose mothers had subnormal oestriol excretion during pregnancy. The incidences of still births, neonatal deaths, dysmaturity and major and minor congenital malformations were significantly increased in pregnancies complicated by one or more subnormal oestriol value. Growth parameters and developmental progress were measured of 136 infants who attained the age of one year, and it was encouraging to find that no gross departures from normal were observed.