Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Crystalloid, colloid or small volume resuscitation?

C Bradley1

  • 1St George's Hospital, London, UK.

Intensive & Critical Care Nursing
|February 28, 2002
PubMed
Summary

Small volume resuscitation (SVR) fluids, combining hypertonic crystalloid and colloid, show promise for trauma patients. Meta-analyses suggest improved survival, but large trials are needed for confirmation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Language Gap: Disparities in Expressive Versus Receptive Language in Young Children With Neurodevelopmental Conditions.

Journal of autism and developmental disorders·2026
Same author

Factor Structure of RRBs in Verbal and Non-Verbal Preschoolers With ASD or Related Characteristics.

Journal of autism and developmental disorders·2025
Same author

State of research, feasibility, safety, acceptability, and outcomes examined on remotely delivered exercises using technology for older adult with cancer: a scoping review.

Journal of cancer survivorship : research and practice·2023
Same author

The radiation dose, clinical and anatomical implications of erect lumbar spine radiography: A single centre pre-post implementation evaluation.

Radiography (London, England : 1995)·2023
Same author

Calibration of an in-situ fluorescence-based sensor platform for reliable BOD<sub>5</sub> measurement in wastewater.

Water science and technology : a journal of the International Association on Water Pollution Research·2021
Same author

Barriers and facilitators related to undertaking physical activities among men with prostate cancer: a scoping review.

Prostate cancer and prostatic diseases·2021

Area of Science:

  • Emergency Medicine
  • Trauma Surgery
  • Critical Care

Background:

  • Small volume resuscitation (SVR) fluids offer logistical advantages in field settings.
  • SVR fluids combine hypertonic crystalloid with colloid for resuscitation.
  • Existing trials suggest potential benefits in trauma and traumatic brain injury.

Purpose of the Study:

  • To evaluate the efficacy of small volume resuscitation fluids in trauma patients.
  • To assess the impact of SVR on inflammatory processes and intensive care outcomes.
  • To determine if meta-analyses reveal survival benefits not apparent in individual trials.

Main Methods:

  • Review of clinical trials and meta-analyses concerning SVR fluid administration.
  • Analysis of outcomes in trauma patients, including those with penetrating injuries and traumatic brain injury.
  • Sub-group analysis to identify specific patient populations benefiting from SVR.

Main Results:

  • SVR fluids demonstrate logistical convenience for field resuscitation.
  • Meta-analyses and sub-group analyses indicate improved survival benefits in trauma patients.
  • Hypertonic saline dextran (HSD) may reduce inflammation and improve intensive care outcomes.

Conclusions:

  • Small volume resuscitation fluids show promise for improving outcomes in trauma care.
  • Survival benefits are most evident through meta-analysis, suggesting a need for larger trials.
  • Further large-scale, blinded, randomized trials are essential to confirm survival advantages.

Related Experiment Videos