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Antiphospholipid syndrome associated with intestinal amoebiasis
C Korkmaz1, E Harmanci, I Metintaş
1Department of Internal Medicine, Medical Faculty, University of Osmangazi, Eskişehir, Turkey. ckorkmaz@ogu.edu.tr
Scandinavian Journal of Infectious Diseases
|March 1, 2002
Summary
This case study reports a rare instance of antiphospholipid syndrome developing after intestinal amoebiasis. The syndrome presented as blood clots, specifically deep vein thrombosis and pulmonary emboli.
Area of Science:
- Infectious Diseases
- Immunology
- Hematology
Background:
- Intestinal amoebiasis is a parasitic infection.
- Antiphospholipid syndrome (APS) is an autoimmune disorder causing blood clots.
Observation:
- A patient developed APS following intestinal amoebiasis.
- Manifestations included deep vein thrombosis and pulmonary emboli.
Findings:
- Elevated IgM and low-titer IgG anticardiolipin antibodies (aCL) were detected post-infection.
- This represents a novel association between amoebiasis and APS.
Implications:
- Highlights a potential trigger for APS in parasitic infections.
- Suggests the need for vigilance in diagnosing APS in patients with amoebiasis.
- Contributes to understanding rare autoimmune complications of infectious diseases.