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Related Experiment Videos

Injection sclerotherapy for varicose veins.

P V Tisi1, C A Beverley

  • 1Department of Vascular Surgery, Bedford Hospital, Kempston Road, Bedford, Bedfordshire, UK, MK42 9DJ. pvtisi@rcsed.ac.uk

The Cochrane Database of Systematic Reviews
|March 1, 2002
PubMed
Summary

Injection sclerotherapy for varicose veins shows no significant difference in efficacy based on sclerosant type or compression methods. Current evidence supports its use for recurrent varicose and thread veins.

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Area of Science:

  • Vascular Surgery
  • Dermatology
  • Phlebology

Background:

  • Injection sclerotherapy has been a widely used treatment for varicose and thread veins since the 1960s.
  • The primary goal is to close off the vein lumen, but evidence on its effectiveness is limited.

Purpose of the Study:

  • To evaluate the efficacy of sclerotherapy for symptomatic and cosmetic improvement of varicose veins.
  • To assess the complication rates associated with the procedure.
  • To determine the recurrence rates of varicose veins after sclerotherapy.

Main Methods:

  • A systematic review of randomized controlled trials (RCTs) comparing injection sclerotherapy for varicose veins was conducted.
  • Searches were performed in EMBASE and MEDLINE databases up to March 2001, supplemented by hand-searching journals and contacting manufacturers.

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  • Included RCTs compared different sclerosants, use of local anesthetic, pressure dressings, and compression bandaging techniques.

    • Main Results:

    • No RCTs directly compared sclerotherapy with non-surgical treatments like compression stockings.
    • Different sclerosants (e.g., sodium tetradecyl sulphate) and compression methods showed no significant differences in efficacy or complication rates.
    • Adding local anesthetic reduced injection pain; compression duration and degree did not impact recurrence, cosmetic appearance, or symptom relief, though increased compression caused discomfort.

    Conclusions:

    • Randomized controlled trial evidence indicates that the type of sclerosant, local pressure dressing, and compression parameters do not significantly affect sclerotherapy's efficacy for varicose veins.
    • These findings support the current clinical use of sclerotherapy, primarily for recurrent varicose veins post-surgery and for thread veins.
    • Further comparative studies, particularly between surgery and sclerotherapy, are warranted.