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Development and evaluation of a graphical anesthesia drug display
Noah D Syroid1, James Agutter, Frank A Drews
1Department of Anesthesiology, School of Medicine, University of Utah, Salt Lake City, Utah 84132-2304, USA. noahs@abl.med.utah.edu
Anesthesiology
|March 2, 2002
Summary
A new graphic display for intravenous anesthetic drugs improved anesthesia management in simulations. Clinicians using the display showed better control over drug concentrations and experienced reduced mental demand, suggesting its utility in clinical practice.
Area of Science:
- Anesthesiology and Bioengineering
- Human-Computer Interaction
- Pharmacology
Background:
- Real-time displays of anesthetic concentrations and effects can improve intraoperative decision-making.
- Pharmacokinetic and pharmacodynamic models exist for estimating drug concentrations and predicting physiological effects.
Purpose of the Study:
- To develop and evaluate a graphic display for real-time intravenous anesthetic concentrations and effects.
- To assess the display's impact on total intravenous anesthesia management.
Main Methods:
- An interdisciplinary team developed a graphic display showing real-time effect-site concentrations and pharmacodynamics of intravenous drugs.
- A computer-based simulation study involved 15 anesthesiologists managing simulated patients with and without the drug display.
Main Results:
- Clinicians using the display administered more remifentanil boluses and maintained drug concentrations closer to the effective concentration 95% (EC(95)).
- Variation in predicted effect-site concentrations for remifentanil and propofol was significantly lower with the display.
- Perceived performance increased, while mental demand, effort, and frustration decreased; no significant differences in simulated heart rate or blood pressure were observed.
Conclusions:
- The developed drug display significantly altered simulated clinical practice.
- The findings suggest promise for this drug data visualization approach, informing future design iterations and evaluations.