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The inflammatory polyp-fold complex in children

Phyllis R Bishop1, Michael J Nowicki, Charu Subramony

  • 1Division of Pediatric Gastroenterology and Nutrition, University of Mississippi Medical Center, Jackson, Mississippi 39216, USA. pbishop@ped.umsmed.edu

Journal of Clinical Gastroenterology
|March 2, 2002
PubMed

Insights

The inflammatory polyp-fold complex (IPFC), a rare finding in children, is linked to reflux esophagitis. Acid suppression therapy may improve IPFC and esophagitis symptoms.

Area of Science:

  • Pediatric Gastroenterology
  • Gastrointestinal Pathology

Background:

  • The inflammatory polyp-fold complex (IPFC) is an uncommon finding in pediatric endoscopy.
  • IPFC involves an inflammatory polyp at the gastroesophageal junction, often continuous with a gastric fold.

Observation:

  • Four pediatric cases of IPFC were identified.
  • All cases were associated with reflux esophagitis.

Findings:

  • Histological examination revealed inflammatory infiltrate in benign gastric and esophageal mucosa.
  • In two patients, acid suppression therapy reduced polyp size and improved esophagitis histologically.

Implications:

  • This study highlights the association between IPFC and reflux esophagitis in children.
  • Acid suppression therapy shows potential for managing IPFC and associated esophagitis in pediatric patients.

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