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[The testing of local electroretinogram in macular diseases]
1Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060.
Objectives:
To record the local electroretinogram (LERG) in macular diseases, and define the using value of LERG in macular diseases.
Methods:
The LERGs of five kinds of maculopathies were recorded with a spot light stimulator at 2.5, 5.0, 7.5 degrees of macular region.
Results:
(1) The amplitudes of LERG at the three regions in Stargardt's disease, wet form age-related macular degeneration (AMD), central serous chorioretinopathy, and idiopathic macular hole were significantly lowered in comparison with the controls (P < 0.01). In the meanwhile, these diseases also showed high abnormal rates. While in dry form AMD and epiretinal membrane, the amplitudes of LERG had no significant changes (P > 0.05). (2) The abnormal rates of LERG were related to the stimulated area. In the three tested areas, the highest abnormal rates occurred at 2.5 degrees.
Conclusions:
There are mean differences in macular electrical activities in these maculopathies. LERG is an effective method of electrophysiology for testing macular function.