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[An experimental study on formation of cellular membrane on the surface of implanted posterior chamber intraocular
1Department of Ophthalmology, The First Teaching Hospital of Norman Bethune Medical University, Changchun 130021.
Objective:
To observe the cellular reaction and membrane formation on the surface of intraocular lens (IOL) implanted in rabbit eyes and discuss the mechanism of early postoperative membrane formation and biological action.
Methods:
20 adult pigmented rabbit eyes were given posterior chamber IOL implantation. IOLs were extracted on the postoperative 1st, 3rd, 7th, 14th and 28th days respectively. Samples were observed under light microscope and scanning electron microscope (SEM).
Results:
Macrophages on the surface of IOL had transformed into fibroblast-like cells and the formation of eosinophilic membrane had occurred on the 3rd day after operation with tiny thread-like things interwoven among cells forming net-like supporting membrane under SEM.
Conclusion:
It infers that the membrane is a kind of fibrinous film secreted by fibroblast-like cells and the cells involved in reaction are the biological foundation of membrane formation; this membrane will prohibit the serious cellular reaction at the end and keep IOL transparent.
