[Long-term results of organ-preserving surgeries for renal cell carcinoma]

The paper presents long-term results of conservative surgical treatment of 148 patients with renal cell carcinoma (RCC). Cancer-specific survival, local recurrence and distant metastases rates were estimated. Overall cancer-specific survival reached 91.8%. For patients with imperative indications this survival was 79.6%, for elective patients--98%. Recurrent RCC was observed in 10(6.8%) patients: imperative group--8(5.4%), elective group--2(1.3%). Distant metastases were detected in 7(4.7%) patients. The elective group had no metastases. General level of multifocality of sporadic renal cancer was 6.7%, for tumors < 4 cm--1.2%. The basic criterion of the decision on organ-saving operation is tumor size under 4 cm. The size of the primary tumor determines the level of local recurrences and distant metastases. To select the optimal group of patients, genetic markers of tumor multifocality should be identified.