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Updated: Feb 9, 2026

A Pipeline to Characterize Structural Heart Defects in the Fetal Mouse
Published on: December 16, 2022
[Ultrasonographic diagnosis of fetal congenital abnormalities]
I Bakon1, J Sikora, T Machalski
1Katedry i Kliniki Połoznictwa i Ginekologii Sl.A.M. w Katowicach-Ligocie.
Retrospective analysis of ultrasonographic examinations in 81 women who delivered newborns with congenital malformations was performed. Totally 147 anatomical defects in 83 newborns were found. 85 of 147 abnormalities (57.8%) were detected prenatally, most commonly (79.6%) in the third-trimester. All cases of coverings defects, as well as, all cases of anencephaly were diagnosed with ultrasonography. Malformations of urinary tract in 94.4%, central nervous system in 82.9%, osteoarticular system in 30%, heart defects in 27.8% and face abnormalities in 21.4% were already sonographically visualized before birth.
Retrospective analysis of ultrasonographic examinations in 81 women who delivered newborns with congenital malformations was performed. Totally 147 anatomical defects in 83 newborns were found. 85 of 147 abnormalities (57.8%) were detected prenatally, most commonly (79.6%) in the third-trimester. All cases of coverings defects, as well as, all cases of anencephaly were diagnosed with ultrasonography. Malformations of urinary tract in 94.4%, central nervous system in 82.9%, osteoarticular system in 30%, heart defects in 27.8% and face abnormalities in 21.4% were already sonographically visualized before birth.
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