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Syntheses of (+/-)-homoepibatidine analogues
Yong-Hyun Kim1, Chang-Young Oh, Kee-Young Lee
1College of Pharmacy, SungKyunKwan University, Suwon, Korea.
Archives of Pharmacal Research
|March 12, 2002
Abstract:
Syntheses of (+/-)-homoepibatidine analogues (2), which contain the 8-azabicyclo [3.2.1]octane ring system, were achieved by using palladium-catalyzed reductive-coupling reaction from 3 and the analgesic activity was tested by Mouse writhing antinociceptive assay.
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