Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Common variable immunodeficiency in children].

M P Llobet1, J M Bertrán, T Español

  • 1Hospital Vall d'Hebron. Unidades de Inmunodeficiencias e Inmunología. Barcelona. Spain.

Allergologia Et Immunopathologia
|March 13, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients.

Clinical and experimental immunology·2013
Same author

Diagnosis of autosomal-dominant hyperimmunoglobulin E syndrome.

Journal of investigational allergology & clinical immunology·2012
Same author

[Spanish Paediatric Infectious Diseases Society consensus document on the treatment of fungal infections based on the immune response].

Anales de pediatria (Barcelona, Spain : 2003)·2010
Same author

A multi-centre study of efficacy and safety of Intratect®, a novel intravenous immunoglobulin preparation.

Clinical and experimental immunology·2010
Same author

Reduced memory B cells in patients with hyper IgE syndrome.

Clinical immunology (Orlando, Fla.)·2008
Same author

Update on the treatment of primary immunodeficiencies.

Allergologia et immunopathologia·2007
Same journal

Peach sublingual immunotherapy for lipid transfer protein syndrome.

Allergologia et immunopathologia·2026
Same journal

Gastrointestinal stenosis: an underrecognized complication of CARMIL2 deficiency.

Allergologia et immunopathologia·2026
Same journal

Peach sublingual immunotherapy for lipid transfer protein syndrome.

Allergologia et immunopathologia·2026
Same journal

Vitamin B12 allergy and desensitization.

Allergologia et immunopathologia·2026
Same journal

Chronic HBV infection, stemness pathways, and compromised immune surveillance in HCC development.

Allergologia et immunopathologia·2026
Same journal

Application of FeNO in the diagnostic and therapeutic algorithm of pediatric asthma: From chronic cough and wheeze to personalized management.

Allergologia et immunopathologia·2026
See all related articles

Common variable immunodeficiency (CVID) in children presents with frequent infections and requires careful diagnosis. Early identification is crucial for effective treatment and preventing long-term complications like bronchiectasis.

Area of Science:

  • Immunology
  • Pediatrics

Context:

  • Common variable immunodeficiency (CVID) is a frequent primary immunodeficiency (PID).
  • It affects a heterogeneous group of patients with varying ages and autosomal recessive inheritance.
  • This study focuses on children diagnosed with CVID at Hospital Infantil Vall d'Hebron.

Purpose:

  • To present a cohort of children diagnosed with CVID.
  • To highlight diagnostic challenges in pediatric CVID cases.
  • To discuss differential diagnoses for recurrent respiratory infections in children.

Summary:

  • Sixteen children (7 months to 15 years) diagnosed with CVID were studied.
  • Diagnosis relies on low immunoglobulin levels and recurrent infections.
  • Differential diagnoses include other PIDs like XLA, X-HIM, IgG subclass deficiency, IgAD, and conditions like cystic fibrosis.

Related Experiment Videos

Impact:

  • CVID patients exhibit a high incidence of respiratory infections and bronchiectasis.
  • Associated allergic and autoimmune conditions are observed.
  • Early diagnosis is vital for initiating appropriate treatment and mitigating infection consequences.