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Postauricular sebaceous carcinoma arising in association with nevus sebaceus
Joseph Rinaggio1, H Stan McGuff, Randal Otto
1Department of Oral Pathology, Biology, and Diagnostic Sciences, Rm. C-829, University of Medicine and Dentistry of New Jersey---New Jersey Dental School, 110 Bergen Street, Newark, NJ 07103-2400, USA.
Background:
Sebaceous carcinoma is an uncommon malignant neoplasm usually associated with the ocular adnexa. Despite the widespread anatomic distribution of sebaceous glands, extraocular sebaceous carcinoma occurs with far less frequency.
Methods:
A 27-year-old man was examined with the presenting complaint of a slowly enlarging subcutaneous mass. It was associated with an overlying, irregular, verrucoid epidermal plaque.
Results:
Histologic and electron microscopic examination of the mass revealed a malignant sebaceous neoplasm occurring in conjunction with an overlying nevus sebaceus. The dermal neoplasm contained numerous cytoplasmic and stromal hyaline globules.
Conclusions:
We report a case of extraocular sebaceous carcinoma arising in the postauricular region in association with a nevus sebaceus and exhibiting the unusual histologic feature of hyaline globules.