[Brain transections for the localization of tremorigenic brain regions in the rat]

In rats transections of the brain have been carried out to localize tremorigenic centres. Ablation of cortical and diencephalic brain areas caused moderate reduction of oxotremorine induced tremor. A makred decrease of tremor intensity has been observed after transections eliminating the tegmental parts of the formation reticularis. We found in caudal sites of transections a shift of the tremor frequency to lower values including changes of distribution as well as the appearance of spontaneous tremor. Both the intensity of oxotremorine induced tremor and the appearance of spontaneous tremor was found to depend on body temperature. Harmine-induced tremor was influenced in opposite direction by ablation of the rostral brain areas.