Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cnidarians as a model system for understanding evolution and regeneration.

Brigitte Galliot1, Volker Schmid

  • 1Department of Zoology and Animal Biology, University of Geneva, Switzerland.

The International Journal of Developmental Biology
|March 21, 2002
PubMed
Summary

Cnidarian animals Hydra and Podocoryne offer unique advantages for studying conserved developmental and regeneration mechanisms. Their accessible life cycles and molecular markers provide insights into pattern formation relevant to bilaterians.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Towards scientific integrity and research ethics adapted to multidisciplinary projects].

Medecine sciences : M/S·2025
Same author

Organizer formation, organizer maintenance and epithelial cell plasticity in Hydra: Role of the Wnt3/β-catenin/TCF/Sp5/Zic4 gene network.

Cells & development·2025
Same author

The <i>Wnt/β-catenin/TCF/Sp5/Zic4</i> Gene Network That Regulates Head Organizer Activity in <i>Hydra</i> Is Differentially Regulated in Epidermis and Gastrodermis.

Biomedicines·2024
Same author

Assessment of Chemical Facility Ethylene Oxide Emissions Using Mobile and Multipoint Monitoring.

Atmospheric Environment: X·2023
Same author

The transcription factor Zic4 promotes tentacle formation and prevents epithelial transdifferentiation in <i>Hydra</i>.

Science advances·2022
Same author

Studying Stem Cell Biology in Intact and Whole-Body Regenerating Hydra by Flow Cytometry.

Methods in molecular biology (Clifton, N.J.)·2022

Area of Science:

  • Developmental Biology
  • Regenerative Medicine
  • Evolutionary Biology

Background:

  • Cnidarians, like Hydra and Podocoryne, possess remarkable regenerative and developmental plasticity.
  • These organisms exhibit conserved molecular mechanisms relevant to broader animal development, including bilaterians.
  • Studying these processes across different life stages (polyp, medusa) offers unique insights.

Purpose of the Study:

  • To leverage Hydra and Podocoryne as model systems for investigating fundamental developmental processes.
  • To analyze molecular cascades involved in regeneration and pattern formation.
  • To explore conserved developmental mechanisms shared across diverse animal phyla.

Main Methods:

  • Comparative analysis of Hydra and Podocoryne.

Related Experiment Videos

  • Study of molecular cascades from amputation to regeneration in Hydra.
  • Investigation of Podocoryne's life cycle, including polyp and medusa stages.
  • In vitro transdifferentiation assays in Podocoryne.
  • Analysis of evolutionarily conserved molecular markers and their regulation.

    • Main Results:

    • Hydra facilitates direct study of regeneration molecular pathways.
    • Podocoryne offers a complete life cycle model with inducible sexual reproduction and in vitro transdifferentiation.
    • Both species provide access to numerous conserved molecular markers.
    • Regulation of these markers highlights underlying pattern formation mechanisms.

    Conclusions:

    • Hydra and Podocoryne are powerful, complementary models for understanding fundamental developmental and regenerative processes.
    • These cnidarians offer insights into conserved molecular mechanisms of pattern formation relevant to bilaterian development.
    • The accessibility of these mechanisms throughout the animals' lives enhances their utility in biological research.