Significance of the human genome sequence to drug discovery

Serum microRNA biomarkers for drug-induced liver injury.

Clinical pharmacology and therapeutics·2012

Assessment of the phototoxic potential of compounds and finished topical products using a human reconstructed epidermis.

In vitro & molecular toxicology·2002

Cytokine expression profiles during murine contact allergy: T helper 2 cytokines are expressed irrespective of the type of contact allergen.

Archives of toxicology·2002

Evidence for the impairment of the vitamin D activation pathway by cyclosporine A.

Biochemical pharmacology·1999

New insights into cyclosporine A nephrotoxicity by proteome analysis.

Electrophoresis·1998

Cyclosporine A-induced decrease in calbindin-D 28 kDa in rat kidney but not in cerebral cortex and cerebellum.

Biochemical pharmacology·1998

Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research.

The pharmacogenomics journal·2026

Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene.

The pharmacogenomics journal·2026

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response.

The pharmacogenomics journal·2026

Large-scale analysis demonstrates the influence of CYP2C19 genotype on specific SSRI side effects.

The pharmacogenomics journal·2026

Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation.

The pharmacogenomics journal·2026

Understanding public perspectives on direct-to-consumer pharmacogenomic testing in the UK: a qualitative study.

The pharmacogenomics journal·2026

Dydrogesterone and inflammatory marker regulation: a systematic review and quantitative meta-analysis.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2026

Prevalence of polypharmacy: a cross-sectional study in Singapore public healthcare institutions.

Singapore medical journal·2026

Cytochrome P450 Enzymes in the Metabolism of Proton Pump Inhibitors: Implications for the Treatment of Peptic Ulcers.

Current drug targets·2026

Effect of Yueju Pill on the Pharmacokinetics and Antidepressant Effect of Fluoxetine in Rats.

Current drug metabolism·2026

Challenges in peri-aortic paraganglioma management.

Journal of surgical case reports·2026

Neuroprotective Effects of Huperzine B and Huperzia carinata Extract Against MPP+-Induced Oxidative Stress in SH-SY5Y Cells.

Advances in pharmacological and pharmaceutical sciences·2026

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Significance of the human genome sequence to drug discovery

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Serum microRNA biomarkers for drug-induced liver injury.

Assessment of the phototoxic potential of compounds and finished topical products using a human reconstructed epidermis.

Cytokine expression profiles during murine contact allergy: T helper 2 cytokines are expressed irrespective of the type of contact allergen.

Evidence for the impairment of the vitamin D activation pathway by cyclosporine A.

New insights into cyclosporine A nephrotoxicity by proteome analysis.

Cyclosporine A-induced decrease in calbindin-D 28 kDa in rat kidney but not in cerebral cortex and cerebellum.

Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research.

Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene.

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response.

Large-scale analysis demonstrates the influence of CYP2C19 genotype on specific SSRI side effects.

Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation.

Understanding public perspectives on direct-to-consumer pharmacogenomic testing in the UK: a qualitative study.

Dydrogesterone and inflammatory marker regulation: a systematic review and quantitative meta-analysis.

Prevalence of polypharmacy: a cross-sectional study in Singapore public healthcare institutions.

Cytochrome P450 Enzymes in the Metabolism of Proton Pump Inhibitors: Implications for the Treatment of Peptic Ulcers.

Effect of Yueju Pill on the Pharmacokinetics and Antidepressant Effect of Fluoxetine in Rats.

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Significance of the human genome sequence to drug discovery

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