Sudden impact? The human genome sequence and the pace of gene discovery in complex diseases

Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation.

medRxiv : the preprint server for health sciences·2021

The Impact of HIV-1 Drug Escape on the Global Treatment Landscape.

Cell host & microbe·2019

Correction: Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Molecular psychiatry·2018

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

Molecular psychiatry·2018

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Molecular psychiatry·2017

Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue.

Scientific reports·2017

Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research.

The pharmacogenomics journal·2026

Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene.

The pharmacogenomics journal·2026

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response.

The pharmacogenomics journal·2026

Large-scale analysis demonstrates the influence of CYP2C19 genotype on specific SSRI side effects.

The pharmacogenomics journal·2026

Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation.

The pharmacogenomics journal·2026

Understanding public perspectives on direct-to-consumer pharmacogenomic testing in the UK: a qualitative study.

The pharmacogenomics journal·2026

Adipocyte-specific deletion of adrenomedullin exacerbates high-fat diet-induced hypertension.

Hypertension research : official journal of the Japanese Society of Hypertension·2026

Gastric bypass and sleeve gastrectomy: Impact on cardiovascular risk factors.

Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis·2026

Establishing personalized reference intervals based on within-subject biological variation using real-world data and the refineR algorithm.

Clinical biochemistry·2026

Peripheral blood glutamate, glutamine, and GABA in Autism Spectrum disorder: A systematic review and meta-analysis of group differences with an exploratory assessment of diagnostic accuracy.

Progress in neuro-psychopharmacology & biological psychiatry·2026

Genetic inference in social insects: The continued utility of microsatellites in the sociogenomic era.

Current opinion in insect science·2026

Towards a Robust cell-free DNA Isolation Protocol for NGS Applications in a Clinical Molecular Diagnostics Setting.

The Journal of molecular diagnostics : JMD·2026

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Sudden impact? The human genome sequence and the pace of gene discovery in complex diseases

Related Concept Videos

Neutralising antibodies in Spike mediated SARS-CoV-2 adaptation.

The Impact of HIV-1 Drug Escape on the Global Treatment Landscape.

Correction: Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia.

Investigation of common, low-frequency and rare genome-wide variation in anorexia nervosa.

Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue.

Barriers and facilitators to the implementation of pharmacogenomic testing for antidepressants use in primary care: a systematic review using the consolidated framework for implementation research.

Amplicon-based long-read sequencing for accurate CYP2D6 gene deletion and duplication detection using CYP2D7 as a reference gene.

Association between CYP2D6 genotype and treatment effectiveness and safety in 99 hospitalized patients with major depressive disorder a retrospective cohort study CYP2D6 genotype and antidepressant response.

Large-scale analysis demonstrates the influence of CYP2C19 genotype on specific SSRI side effects.

Effects of CYP3A4, CYP3A5, and ABCB1 genetic variants on tacrolimus metabolism during the early period after kidney transplantation.

Understanding public perspectives on direct-to-consumer pharmacogenomic testing in the UK: a qualitative study.

Adipocyte-specific deletion of adrenomedullin exacerbates high-fat diet-induced hypertension.

Gastric bypass and sleeve gastrectomy: Impact on cardiovascular risk factors.

Establishing personalized reference intervals based on within-subject biological variation using real-world data and the refineR algorithm.

Peripheral blood glutamate, glutamine, and GABA in Autism Spectrum disorder: A systematic review and meta-analysis of group differences with an exploratory assessment of diagnostic accuracy.

Genetic inference in social insects: The continued utility of microsatellites in the sociogenomic era.

Towards a Robust cell-free DNA Isolation Protocol for NGS Applications in a Clinical Molecular Diagnostics Setting.

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Sudden impact? The human genome sequence and the pace of gene discovery in complex diseases

Related Concept Videos

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