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Drug eruptions and other adverse drug effects in aged skin
John R Sullivan1, Neil H Shear
1Drug Safety Clinic, Department of Medicine, University of Toronto Medical School, Ontario, Canada.
Abstract:
The elderly are at higher risk for suffering the annoying and hazardous skin reactions that are associated with drug therapy. If a serious reaction occurs, the aged are also at higher risk for major morbidity and mortality compared with younger individuals. Early consideration of a drug cause and prompt cessation of all potentially associated drugs may improve a patient's outcome. Thus, a prompt, careful, and accurate characterization of a drug-related reaction is important in optimizing patient care, along with close monitoring for associated internal toxicities and other medical complications of severe cutaneous reactions.