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Antimicrobial use prior to the acquisition of multiresistant bacteria
Matthieu Eveillard1, Jean-Luc Schmit, François Eb
1Department of Bacteriology, Hygiene and Infection Control, Hôpital Nord, Amiens, France.
Infection Control and Hospital Epidemiology
|March 29, 2002
Abstract:
We assessed whether patients who acquired methicillin-resistant Staphylococcus aureus (MRSA) had less exposure to antimicrobial agents than did those who acquired Enterobacteriaceae that produced extended-spectrum beta-lactamase (ESbetaL). In a 6-month, prospective study, ESbetaL carriers had received antimicrobial therapy more often than had MRSA carriers. Amoxicillin-clavulanic acid, fluoroquinolones, and third-generation cephalosporins, especially ceftazidime, had been prescribed more often for ESbetaL carriers than for MRSA carriers.