Jove
Visualize
Contact Us

Related Experiment Videos

Pediatric partial and generalized seizures.

Martina Bebin1

  • 1North Alabama Children's Specialists, Huntsville 35801, USA. ebebin@peds.uab.edu

Journal of Child Neurology
|March 29, 2002
PubMed
Summary

Eight new anticonvulsant drugs offer more treatment options for pediatric epilepsy. However, limited pediatric data exists for these newer antiepilepsy drugs, necessitating further research on their safety and efficacy in children.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mood and Anxiety Disorders and Suicidality in Patients With Newly Diagnosed Focal Epilepsy: An Analysis of a Complex Comorbidity.

Neurology·2025
Same author

It's About Time! Timing in Epilepsy Evaluation and Treatment.

Epilepsy currents·2024
Same author

<i>ARF1</i>-related disorder: phenotypic and molecular spectrum.

Journal of medical genetics·2023
Same author

Mood and Anxiety Disorders and Suicidality in Patients With Newly Diagnosed Focal Epilepsy: An Analysis of a Complex Comorbidity.

Neurology·2022
Same author

Profile of Autism Spectrum Disorder in Tuberous Sclerosis Complex: Results from a Longitudinal, Prospective, Multisite Study.

Annals of neurology·2021
Same author

Antiepileptogenesis and disease modification: Clinical and regulatory issues.

Epilepsia open·2021
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Neurology
  • Pediatric Epilepsy

Background:

  • Since 1993, eight new anticonvulsant medications have been approved in the U.S.
  • These offer expanded treatment options for pediatric partial and generalized seizures.
  • Limited pediatric pharmacokinetic and pharmacodynamic data is available for these newer agents.

Purpose of the Study:

  • To review newer antiepilepsy drugs approved since 1993.
  • To summarize current knowledge on the safety and efficacy of these drugs in pediatric populations.
  • To identify gaps in pediatric data for these medications.

Main Methods:

  • Literature review of newer antiepilepsy drugs.
  • Focus on gabapentin, felbamate, lamotrigine, topiramate, oxcarbazepine, levetiracetam, and zonisamide.
  • Summary of existing pediatric safety and efficacy data.

Main Results:

  • Newer anticonvulsants provide more therapeutic choices for pediatric epilepsy.
  • Information on the specific use of these drugs in children remains limited.
  • Data on pharmacokinetics and pharmacodynamics in pediatric populations is scarce.

Conclusions:

  • Further research is essential to fully assess the efficacy and safety of these newer antiepilepsy drugs in children.
  • Pediatric neurologists require more comprehensive data for informed treatment decisions.
  • The review highlights the need for dedicated pediatric studies on these medications.

Related Experiment Videos