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IL-2 mediates adjuvant effect of dendritic cells

Francesca Granucci1, Daniel M Andrews, Mariapia A Degli-Esposti

  • 1Dept of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, Milan, Italy.

Trends in Immunology
|March 30, 2002
PubMed
Summary

Dendritic cells (DCs) are key immune cells that link innate and adaptive immunity by producing interleukin-2 (IL-2). Murine cytomegalovirus can disrupt this crucial IL-2 production and T cell priming.

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