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[Advanced sleep phase syndrome].

B Ondzé1, F Espa, L C Ming

  • 1Service de Neurologie B, Unité des Troubles du Sommeil et de l'Eveil, Hôpital Gui-de-Chauliac, 80, Av. Augustin Fliche, 34295 Montpellier. Agnaneme@aol.com

Revue Neurologique
|April 2, 2002
PubMed
Summary
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Advanced Sleep Phase Syndrome (ASPS) is a circadian rhythm disorder with early sleep times. Management is challenging, with light therapy offering temporary improvement for some patients.

Area of Science:

  • Chronobiology
  • Sleep Medicine

Context:

  • Advanced Sleep Phase Syndrome (ASPS) is a circadian rhythm disorder characterized by early sleep onset and awakening.
  • Diagnosis involves clinical and laboratory investigations to confirm phase advance in body temperature and melatonin rhythms.

Purpose:

  • To investigate the clinical and laboratory findings in patients diagnosed with Advanced Sleep Phase Syndrome (ASPS).
  • To evaluate the effectiveness of management strategies including light therapy and chronotherapy.

Summary:

  • Seven patients (aged 15-72) with ASPS were studied using sleep logs, actigraphy, and polysomnography.
  • Investigations confirmed advanced body core temperature nadir (01:38) and melatonin/cortisol rhythms.
  • Familial cases were identified, and temporary improvements were observed with light therapy and chronotherapy.

Related Experiment Videos

Impact:

  • Highlights the diagnostic challenges and variable treatment outcomes for ASPS.
  • Emphasizes the need for further research into effective management of this rare sleep disorder.