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Updated: Aug 4, 2026

Quantification of Orofacial Phenotypes in Xenopus
Published on: November 6, 2014
[Cleft lip and palate: thoughts about associated anomalies]
1Afdeling Anthropogenetica, Academisch Ziekenhuis Nijmegen, Centrum voor Schisis en Craniofaciale Afwijkingen, Faculteit der Medische Wetenschappen, Katholieke Universiteit Nijmegen.
Abstract:
During two years all new patients referred to the cleft palate team in Nijmegen, were examined by a clinical dentist, to evaluate the occurrence of associated anomalies or syndromes. In 33% of the patients with all types of clefts associated anomalies were found. A percentage of 56% was found for cleft palate only, and of 14% for cleft lip (palate). It is important to make a classifying diagnosis of these associated anomalies because they may have important implications for recurrence risks and prognosis. The percentage of associated anomalies is the highest in the group of patients with cleft palate only or submucous clefts. Therefore, the dentists have to be aware of the presence of submucous clefts and their consequences.

