The spectrum of subdivided left atrium: diagnosis, treatment and outcome in eight patients
Related Experiment Video
Updated: Oct 1, 2026

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China
Published on: February 11, 2022
Walter Knirsch1, Martin A G Lewin, Joachim G Rein
1Department of Pediatric Cardiology and Pediatric Intensive Care, Olgahospital, Stuttgart, Germany. w.knirsch@olgahospital.de
Insights
Subdivided left atrium in infants can cause failure to thrive and cardiac issues. Surgical intervention offers good short- and intermediate-term outcomes for most patients, improving recovery from pulmonary hypertension.
Area of Science:
- Pediatric Cardiology
- Congenital Heart Disease
- Cardiac Surgery
Background:
- Subdivided left atrium is a rare congenital heart anomaly.
- It presents with significant clinical challenges in infants, including failure to thrive and congestive cardiac failure.
Purpose of the Study:
- To evaluate the clinical presentation, diagnostic methods, and surgical outcomes of infants with subdivided left atrium.
- To assess the short- and intermediate-term results of surgical management in this patient population.
Main Methods:
- Retrospective review of eight patients diagnosed with subdivided left atrium between January 1996 and April 2001.
- Diagnosis confirmed by transthoracic echocardiography; cardiac catheterization used selectively.
- Surgical intervention performed in seven patients.
Main Results:
- Transthoracic echocardiography was diagnostic in all cases.
- Six out of seven surgically treated patients showed good short- and intermediate-term outcomes (mean follow-up 34.3 months).
- Postoperative improvements included thriving, reduced respiratory infections, absence of significant arrhythmias, and recovery from pulmonary hypertension and right ventricular hypertrophy.
Conclusions:
- Subdivided left atrium requires prompt diagnosis and surgical management.
- Surgical treatment leads to favorable outcomes, including resolution of pulmonary hypertension and improved overall health in surviving infants.
Abstract:
From January 1996 to April 2001, we treated eight patients with subdivided left atrium. Their ages at diagnosis ranged from newborn to 6.4 years. Prominent clinical symptoms were failure to thrive, respiratory symptoms, demand for oxygen, and congestive cardiac failure. Diagnosis was made by transthoracic echocardiography in all cases. Cardiac catheterization was necessary only in those patients who had associated cardiac anomalies, or suspected signs of pulmonary hypertension. In 7 patients, surgery was performed immediately after diagnosis, but one preterm infant died before operation due to neonatal sepsis and respiratory distress syndrome. In the postoperative period, one patient developed a severe capillary leak syndrome, and died due to irreversible congestive cardiac failure. The other 6 patients have all been followed up, with good results in the short- and intermediate-term at a mean of 34.3+/-20.2 months. The infants were thriving, had a reduction in the frequency of infections of the respiratory tract, no significant arrhythmias, and showed early recovery from pulmonary hypertension and right ventricular hypertrophy.
Related Concept Videos
Mitral Stenosis II: Clinical features and Diagnostic Tests
Mitral Regurgitation II: Clinical Features and Diagnostic Tests
Acute Coronary Syndrome III: Diagnostic Studies
Cardiac Catheterization II: Right Heart Catheterization
Aortic Regurgitation II: Clinical Features and Diagnostic Tests
Mitral Regurgitation III: Medical Management
